Charcot-Marie-Tooth disease pathophysiology
CMT is a motor and sensory neuropathy characterized by the progressive loss of movement, muscle tissue and the sense of touch. Among other possible agents, it is caused by the deficiency of GDAP1, a mitochondrial membrane protein. This figure summarizes the roles of GDAP1 in neurons, as well as the pathological effects originated by its […]
CMT is a motor and sensory neuropathy characterized by the progressive loss of movement, muscle tissue and the sense of touch.
Among other possible agents, it is caused by the deficiency of GDAP1, a mitochondrial membrane protein.
This figure summarizes the roles of GDAP1 in neurons, as well as the pathological effects originated by its deficiency.
2018. Private order.
